| 摘要: |
| 采用冷渗漉提取的方法提取马兰的化学成分。经硅胶柱色谱和Sephadex LH 20进行分离纯化，通过理化方法和波谱数据分析进行结构鉴定。从80%乙醇冷渗漉提取物的水不溶物中分离并鉴定了12个化合物，分别为正十六烷酸（1）、6 羟基 桉烷 4（14） 烯（2）、β 谷甾醇（3）、α 菠菜甾醇（4）、香草醛（5）、β 20(21)，24 二烯 达玛烷 3 酮（6）、豆甾醇（7）、木栓酮（8）、羽扇豆酮（9）、α 香树脂醇（10）、表木栓醇（11）、神经酰胺（12）。化合物2、6、9、12均为首次从该种植物中分得。 |
| 关键词: 马兰 渗漉提取 分离鉴定 化学成分 |
| DOI： |
| 分类号:Q946 |
| 基金项目: |
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| Studies on the chemical constituents of Kalimeris indica （Ⅱ） |
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ZHONG WenWu， LIU JinSong， ZHANG CongEr， CHEN AiMin， XU YingSheng， WANG Gang*
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School of Materia Madica， Anhui University of Traditional Chinese Medicine， Anhui Key Laboratory of Modernized Chinese Material Medical， Hefei 230031， China
School of Materia Madica， Anhui University of Traditional Chinese Medicine， Anhui Key Laboratory of Modernized Chinese Material Medical， Hefei 230031， China
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| Abstract: |
| The chemical constituents were extracted from Kalimeris indica by cold percolation extraction .Compounds were isolated and purified with silica gel and Sephadex LH 20 column chromatography，the structures were determined on the basis of physicochemical evidence and ectroscopic analysis. Twelve compounds were separated and purified from water insoluble parts of 80% alcohol extracts of K.indica. They were identified as n Hexadecanioc acid（1）、6 Hydroxy eudesm 4(14) ene（2）、β Sitosterol（3）、α Spinasterol（4）、Vanillin（5）、3 Oxo dammara 20(21)，24 dene（6）、Stigmasterol（7）、Friedelin（8）、Lupeone（9）、α Amyrin（10）、Friedel 3 ol（11）、（2S，3S，4R，8E） 2 [(2R′) 2′ Hydroxyteracosenoilamino] 8 octadecene 1，3，4 triol（12）. Compounds 2、6、9、12 were isolated from this plant for the first time. |
| Key words: Kalimeris indica percolation process isolation and structure identification chemical constituents |
